Frontiers Paracetamol Induced Glutathione Consumption: Is There a Link With Severe COVID 19 Illness? NAPQI Wikipedia Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Acetaminophen metabolism Researchers are studying a possible link between acetaminophen (Tylenol) use during pregnancy and higher autism or ADHD risk. It may lower glutathione, an important antioxidant for brain development.